(1-Isopropyl-1H-Pyrazol-5-YL)Boronic Acid Pinacol Ester

(1-Isopropyl-1H-Pyrazol-5-YL)Boronic Acid Pinacol Ester - Names and Identifiers

Name	1-Isopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Synonyms	1-Isopropylpyrazole-5-boronic Acid Pinacol Ester 1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester (1-Isopropyl-1H-Pyrazol-5-YL)Boronic Acid Pinacol Ester 1-Isopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) 1-propan-2-yl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole 1-Isopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 1-Isopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 1-(1-Methylethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 3-hydroxy-2,3-dimethylbutan-2-yl hydrogen (1-isopropyl-1H-pyrazol-5-yl)boronate
CAS	1282518-60-8
InChI	InChI=1S/C12H21BN2O2/c1-9(2)15-10(7-8-14-15)13-16-11(3,4)12(5,6)17-13/h7-9H,1-6H3

(1-Isopropyl-1H-Pyrazol-5-YL)Boronic Acid Pinacol Ester - Physico-chemical Properties

Molecular Formula	C12H21BN2O2
Molar Mass	236.12
Density	1.03±0.1 g/cm3(Predicted)
Boling Point	327.3±15.0 °C(Predicted)
Flash Point	151.7±20.4 °C
Vapor Presure	0.0±0.7 mmHg at 25°C
pKa	1.98±0.10(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.503

(1-Isopropyl-1H-Pyrazol-5-YL)Boronic Acid Pinacol Ester - Introduction

1-Isopropylpyrazole-5-boronic acid pinacol ester is an organic compound that has the following properties and uses:

Nature:
-Appearance as a white crystalline solid.
-The molecular formula is C11H19BN2O4 and the relative molecular mass is 254.08.
-Soluble in common organic solvents such as ethanol and dimethylformamide.
-At elevated temperature, 1-isopropylpyrazole-5-boronic acid pinacol ester may decompose.

Use:
-1-isopropylpyrazole-5-boronic acid pinacol ester is an organic borate, which is widely used as a hydrogen donor and base catalyst in organic synthesis.
-It can be used in various organic reactions such as alcohol alkylation reaction and reduction reaction.
-It can also be used as a synthetic intermediate for optical materials and liquid crystal substances.

Preparation Method:
-1-isopropylpyrazole-5-boronic acid pinacol ester synthesis method is more complex, a commonly used method is through the pyrazole and isopropanol in the presence of sodium carbonate reaction to generate 1-isopropylpyrazole, and then with three (methyl) boronic acid aldehyde reaction, and finally dehydration to generate the target product.

Safety Information:
-1-isopropylpyrazole-5-boronic acid pinacol ester is safe, but it is still necessary to take appropriate safety measures.
-use should wear chemical protective glasses and gloves, avoid direct contact and inhalation.
-Avoid dust and particulate matter to avoid affecting the respiratory system.
-Avoid contact with strong oxidants and strong acids during storage and handling.
-For more detailed safety information, please refer to the relevant safety technical instructions or consult a professional.

Last Update：2024-04-10 22:29:15